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Shipyard Employees: Asbestos has actually been typically utilized in shipbuilding due to its durability and heat-resistant properties. Workers in the shipbuilding industry are at a high danger of direct exposure, as materials with asbestos might still be utilized. You might get approved for compensation if your employer's neglect resulted in direct exposure to asbestos.
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GOALS: Primary Determine the impact of pazopanib hydrochloride on the proportion of clients with malignant pleural mesothelioma who are progression-free at 6 months based upon the RECIST criteria. Identify the medical toxicities of this drug in this patient population. Secondary Determine the unbiased tumor reaction status in these patients as determined by the RECIST criteria or the modified RECIST criteria.
Identify the result of this drug on overall survival and time to development in these clients. Examine predictive markers of activity of this drug in these patients. Assess serologic markers of target inhibition by this drug in these patients. LAY OUT: This is a multicenter study. Patients receive oral pazopanib hydrochloride once daily on days 1-21.